cellcrusher

Why are the Cellcrusher’s surfaces curved?

The Cellcrusher’s curved surfaces facilitate easy sample recovery and cleaning. The ergonomic design of the device and accessories allow for manipulation of the device at liquid nitrogen temperatures.Previously, cell disruption with other pulverizers involved loss of valuable sample and use of awkward freezer gloves, due to right-angled surfaces and other design shortcomings.

How do you cryopulverize very small samples?

As tissue sample size shrinks, recovering miniscule amounts of frozen powder and transferring into buffer becomes more difficult. The Cellcrusher-mini is our patent-pending solution.

How do you cryogenically disrupt dry or difficult tissue types?

Cell disruption by cryo-impacting relies to a certain extent on the presence of water inside the sample. In simple terms, ice adds “brittleness” to the sample and microfractures in the ice help shear cell membranes. Therefore, dry tissues such as seeds (such as maize, wheat and rice) or bark can be difficult to break by impact alone.