Libin Ye Lab

Name: Libin Ye Lab - AI Visibility Score
Creator: Engagemii
Published: 2026-07-06T20:56:43.150Z
License: https://creativecommons.org/licenses/by/4.0/

Unclaimed

AEO Score: 5/10

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libinye.com

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5/10 means Libin Ye Lab is borderline visible. AI bots can crawl your site but your structured-data signals are thin. You are at risk of being skipped when buyers ask AI for a recommendation.

About Libin Ye Lab

GPCR conformational transition and dynamics as well as signaling; membrane proteins; www.libinye.com

Key Topics

We are developing NMR spectroscopic and biological tools to map and quantify the conformational landscape of membrane proteins such as GPCRs. These breakthroughs enable us to study the roles of individual conformational states, their transitions, and dynamics, and thus, the impacts on signaling efficacies and biases. Our ultimate goal is to create precise medications that target a specific disease-related conformation, rather than the entire protein, with minimal side effects.

2. GPCR and Diseases We study a set of disease-related GPCRs to understand their activations using BRET, cryo-EM, and MD simulation, complemented by our primary tool, 19F-qNMR, for better drug development. We're currently concentrating on GPCRs linked to neurological, cardiovascular, and obesity-related diseases, including adenosine receptors, GLP-1R/GCGR receptors, PAC1R, and adenylyl cyclases.

We also study a set of dinoflagellate GPCRs related to the occurrence of red tide blooms. Our vision for this line of research is to unravel the role of GPCRs in the bioluminescent signaling process. Our goal includes exploring tools in modulating dinoflagellate bioluminescence that often damages coastal ecosystems and causes public health concerns after consuming seafood contaminated by red tide algae. We also aim to understand the evolutionary role of unicellular GPCRs. Towards this, most recently, we identified the first wave-sensitive receptor that illuminates the ocean at night, named as BIR1.