MK-1242 VALOR Study - Merck Clinical Trials

Who can join the VALOR Study?

There will be about 342 participants from around the world. Children with heart failure who are between the ages of 29 days to 17 years (before 18th birthday) may be eligible to join the study. There are other requirements to join the study. Your child’s cardiologist can help you decide if your child may be eligible.

What happens during the VALOR Study?

The study lasts about 1 year. It has three parts. In total, there will be about 12 scheduled visits to the study clinic.

What happens at study visits?

Your child will have health checks and tests at study visits. The study doctor will also talk to you and your child and ask questions. The information will help the researchers understand if the study medicine may safely help children with heart failure. You’ll be familiar with most of the tests. Some tests will only be done a few times during the study.

What is the study medicine?

The study medicine, vericiguat, is being compared to a placebo. The placebo looks just like vericiguat, but has no active ingredients. The study medicine comes as a liquid or tablet to be taken once a day with food. Whether your child gets the liquid or tablet will depend on their weight. The medicine should be taken approximately at the same time each day (about every 24 hours).

What can you do next?

If you are interested in your child taking part in this clinical study, please take the next step to see if your child may be eligible. Discuss with your child’s doctor or care team Print this page with details about the study or email it to your child’s doctor to discuss the clinical study during your child’s next visit.